The "Forum on Exploration and Development of Comprehensive Therapy for Cancer" in 2018, sponsored by our hospital, was solemnly held on January 27, 2018 in the academic lecture hall on the 4th floor of Building 1 of our hospital. Director Liu Hua of Medical Administration Department of Shanghai University of Traditional Chinese Medicine attended the meeting on behalf of President Xu Jiaguang. President Zhou Jia of our hospital delivered a speech at the meeting.

Mutation of specific genes is a key factor in tumorigenesis and development. With the discovery and clinical success of targeted drugs targeting specific genes, cancer therapy has opened an era of precise treatment.Recent studies have found that cancer is not only a mutation-related disease, but also a metabolic disease.Tumor cells acquire molecular materials and energy substances necessary to support malignant proliferation through unusual metabolic pathways. Intervention of metabolic characteristics in the microenvironment of tumor tissues can promote or inhibit the deterioration of tumors.Therefore, metabolic regulation therapy, with the main strategy of correcting or interfering with the metabolism of tumors, has become a new hotspot of international concern and the sixth cancer treatment method after surgery, chemotherapy, radiotherapy, Traditional Chinese Medicine and bio-immunotherapy.

How to adopt appropriate comprehensive treatment measures based on precise treatment and metabolic therapy to achieve the goal of curing cancer has ushered in a new breakthrough point for cancer treatment. This forum focuses on this breakthrough point, bringing together the latest achievements of theoretical, clinical and basic research in cancer metabolism and precise treatment. This forum focuses on this breakthrough point, bringing together the latest achievements of theoretical, clinical and basic research in cancer metabolism and precise treatment.It includes the new ideas of metabolic regulation in cancer therapy, the new progress of anti-tumor molecular target discovery and targeted therapy, and the new discovery of microRNA in metabolic remodeling.At the same time, the Forum reported in-depth on the new attempts of "cocktail" therapy for prostate cancer combined with metabolic regulation supporting chemotherapy, multidirectional therapy for glioblastoma and other cancers, and comprehensive therapy for cancer under the principle of anti-aging functional medicine.More importantly, the forum shows the new development of TCM treatment in the era of precise and metabolic therapy, the role of TCM nursing in cancer treatment, including dietary regulation, the impact of targeted therapy on TCM syndrome differentiation and treatment, comprehensive treatment of post-operative metastasis of colorectal cancer and intervention strategies of TCM.These hot spots aroused great interest of participants.

Professor Thomas N. Seyfried of Boston College of Biology, Dr. Yu Gong of UrologyDepartment, George Washington University School of Medicine, Dr. N Daba Mazibuko of King's College of London, Care Cancer Clinic, Research Fellow of American Academy of Anti-Aging and Regenerative Medicine, and Research Fellow of A4M Cancer Comprehensive Treatment Department, Dr. Cheng Chang, founder and director of Cheng's Comprehensive Health Center in Columbia, USA, were invited to the forum to deliver brilliant speeches at the meeting. At the same time, well-known domestic oncology clinical and research experts were invited to attend the meeting and exchange, including the special researcher of Shanghai Institute of Life Sciences, Chinese Academy of Sciences, Dr. Ying Hao of Shanghai Institute of Cell Biology, Director of Oncology Department, Shu Guang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Professor Li Qi, Chairman of the World Federation of Cancer Precision Professional Committee, and Jia Lijun from Longhua Hospital, Director of Institute of Traditional Chinese Medicine and Oncology Research Institute of Shanghai Academy of Traditional Chinese Medicine, Professor Xu Ling, Director of Oncology Department of our Hospital, etc. This forum is a grand event in the field of cancer metabolism of integrated Chinese and Western medicine at home and abroad.

At the meeting, Professor Xu Ling's report "Rethinking the Integration of Traditional Chinese and Western Medicine for Lung Cancer in the Era of Precision Therapy" received strong repercussions.Professor Xu Ling pointed out that the use of targeted drugs in the era of precise cancer treatment posed a challenge to the combined treatment of Traditional Chinese Medicine. Targeted drugs have good curative effect, but drug resistance is unavoidable. The symptoms of patients with side effects are similar. Therefore, under precise treatment, the thinking mode of TCM syndrome differentiation should be broadened. For example, the cold and heat attributes of targeted drugs can be distinguished, and the location of tumors, pathological types, growth rate, duration of disease can be used as the basis of differentiation of symptoms and signs.At the same time, different intervention strategies of Traditional Chinese Medicine were adopted in different stages of targeted drug treatment, and the combination of disease and syndrome to give certain drugs was adopted to achieve the best effect by stratified intervention and physical and mental treatment.

The forum covers the application of functional medicine, anti-aging medicine, hormone replacement therapy and Traditional Chinese Medicine in the metabolic and precise treatment of prostate cancer, lung cancer and colorectal cancer. It spans many fields such as oncology biology and oncology clinic. This forum brings together the elites who are devoted to the clinical and research of comprehensive cancer therapy. Through cross-linking, mutual intelligence and collaboration, we can improve the level of comprehensive cancer therapy, which will certainly promote the development of cancer treatment.